The EuroSIDA study also shows that HIV positive patients who started the cART therapy with a CD4 cell count of above 350 cells per microlitre of blood had CD4 cells counts approaching the level seen in HIV-negative individuals after more than three years of cART therapy.

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Die EuroSIDA-Studie zeigte auch, dass bei HIV-positiven Patienten mit einer Zahl von über 350 CD4-Zellen je Mikroliter Blut zu Therapiebeginn die CD4-Zellen nach über drei Jahren cART-Therapie dem Wert bei HIV-negativen Personen entsprachen.

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The only patients who did not show a substantial increase in their CD4 cell count where those who had undergone the cART therapy for more than five years with an average CD4 cell count of more than 500 cells per microlitre of blood at the start of the treatment.

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Nur bei den Patienten, die bereits seit über fünf Jahren eine cART-Therapie mit einer Anzahl von durchschnittlich über 500 CD4-Zellen je Mikroliter Blut zu Behandlungsbeginn durchlaufen hatten, war kein deutlicher Anstieg festzustellen.

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It is interesting to note however that HIV positive patients who started the cART therapy with a low CD4 cell count (less than 200 cells per microlitre) had substantial rises in CD4 counts even after five years.

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Interessant war jedoch festzustellen, dass bei HIV-positiven Patienten mit einer niedrigen Zahl von CD4-Zellen zu Therapiebeginn (weniger als 200 Zellen je Mikroliter) die CD4-Zellen sogar noch nach fünf Jahren stark anstiegen.

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The authors of the EuroSIDA study, Dr Amanda Mocroft of the Royal Free and University College London Medical Schools, and Prof Jens D. Lundgren, University of Copenhagen, can therefore conclude that a normalisation of the CD4 cell count in the blood of HIV-infected patients can be achieved if viral suppression with the cART therapy can be maintained for a sufficiently long period of time. The EuroSIDA study has shown that most HIV positive patients who can maintain a viral load at less than 50 copies per ml of blood continue to have significant rises in their CD4 cell counts even after five years of cART treatment.

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Die EuroSIDA-Studie hat gezeigt, dass bei den meisten HIV-positiven Patienten, die die Virenlast unter 50 Kopien je ml Blut halten können, ein fortgesetzt deutlicher Anstieg der CD4-Zellen auch noch nach fünf Jahren cART-Behandlung festzustellen ist.

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In the 1835 patients studied, the CD4 cell count was on average 204 cells per microlitre of blood, as they started the cART treatment.

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Bei den 1835 Patienten, die an der Studie teilnahmen, wurden bei Beginn der cART-Behandlung im Durchschnitt 204 CD4-Zellen je Mikroliter Blut gezählt.

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Date index: 2023-12-20